There are no VISTA audio CODEC drivers to support the MW12cx mixer. I have a Toshiba M115-S3144 with Windows Vista. the Cubase AI4 updates don't cover the issue, the Yamaha ASIODKS_MW102 driver that is listed on the Yamaha web site as applicable to Vista is listed in it's (ASIODKS) documentation as an XP driver and will not install in Vista. The Realtek driver V 1.90 doesn't cover the issue either. I am unable to find a driver that will work.